Side-by-Side Comparison

Mounjaro vs Ozempic

Both for type 2 diabetes. Mounjaro (tirzepatide) demonstrates superior glycemic control and ~47% greater weight loss in the SURPASS-2 head-to-head trial vs Ozempic (semaglutide).

Dr. Parmis - Medical Researcher
Researched By
Dr. Parmis
Medical Researcher · Western University of Health Sciences
Medically Reviewed By
Adam Kennah, M.D.
Board-Certified Physician
Last clinically reviewed: April 28, 2026 · This page is informational and does not constitute medical advice.

Comparison summary

Both for type 2 diabetes. Mounjaro (tirzepatide) demonstrates superior glycemic control and ~47% greater weight loss in the SURPASS-2 head-to-head trial vs Ozempic (semaglutide).

For the full clinical evidence, see clinical research and main comparison page.

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